How to win with the prion in brutal mode in Plague Inc.

The Brutal mode in Plague Inc. is the highest difficulty level of the game, where the player must face greater challenges compared to other modes. In this mode, the prion is one of the most difficult diseases to manage and win with.

The prion is a highly mutative virus that can spread quickly and cause irreparable damage to the patient's organs. To win with the prion in Brutal mode, you must be very strategic and have a detailed plan from the beginning.

In this article, I'll provide you with some useful information on how to win with the prion in Brutal mode in Plague Inc., including how to select the right abilities and how to manage the spread of the disease.

How does Brutal mode work?

In Brutal mode, governments are much more attentive to the spread of disease and have a greater chance of developing effective cures and vaccines. Additionally, patients are also more resistant to diseases and can survive longer compared to other modes.

However, not everything is negative in Brutal mode. The player has access to unique abilities that can help spread the disease faster or reduce the effectiveness of cures developed by governments.

  • Transmission abilities: these abilities help spread the disease through various means such as air, water or animals. Choosing the right transmission abilities is crucial for rapidly spreading prion.
  • Genetic abilities: these abilities influence the prion's ability to mutate and adapt to environmental conditions. The right genetic abilities can improve disease survival and make it more resistant to cures developed by governments.
  • Symptom abilities: these abilities determine the symptoms that the patient develops during the disease. Choosing the right symptoms can help hide the presence of prion and prevent governments from developing an effective cure.

Now that you have a general idea of how Brutal mode works, let's see how to manage the prion in this difficulty.

Basic strategies for prion in Plague Inc.

The prion is one of the most difficult diseases to manage in Plague Inc., but with the right strategies, you can win even in Brutal mode. Here are some basic strategies that will help you achieve victory:

Choose the right country

Choosing the right country is crucial when playing with prion. You should look for a country with a high population density and weak healthcare system. This way, your disease can spread quickly without being detected too soon.

Be careful with mutations

Mutations are important in the game of prion, but you must be careful not to make too many or too early. The first mutations should be those that increase disease transmission, such as transmission through air or parasites. Only after spreading the disease widely enough should you focus on mutations that increase its lethality.

Use symptoms to your advantage

Symptoms can be used to your advantage when playing with the prion. For example, you can choose symptoms that make it difficult to detect the disease, such as mild fever or dry cough. This way, the disease can spread further without being detected too early.

Use special abilities wisely

Special abilities can be used to increase the spread and lethality of the disease, but they must be used wisely. For example, you can use the "Drug Resistance" ability only when countries start developing cures for your disease. This way, your disease will continue to spread even after the first cures have been developed.

  • Choose the right country
  • Watch out for mutations
  • Use symptoms to your advantage
  • Use special abilities wisely

Remember that prion is one of the most difficult diseases to manage in Plague Inc., but by following these basic strategies, you can increase your chances of winning even in brutal mode. Good luck!

How to evolve your prion effectively

Evolving your prion effectively is crucial to winning in Plague Inc. There are many options available, but here we will focus on the most effective strategies.

Phase 1: Symptom evolution

The first thing to do is to evolve your prion's symptoms. Start with less lethal symptoms and spread them as much as possible. This will make it easier for your prion to spread without attracting the attention of health authorities.

  • Start with symptoms like coughing and sneezing, which are easily transmitted through direct contact.
  • Next, add symptoms like fever and sweating to increase the severity of the disease.
  • Finally, evolve the most lethal symptoms like organ failure and internal bleeding only when you have infected enough people.

Phase 2: Transmission ability evolution

After evolving the symptoms, you need to focus on spreading your prion. Evolve transmission abilities to reach as many people as possible.

  • Start with airborne transmission, which allows you to spread the prion through the air.
  • Next, evolve waterborne and parasite transmission to reach even those living in isolated areas.
  • Finally, evolve bloodborne transmission to infect those who come into contact with infected bodily fluids.

Phase 3: Resistance evolution

Once you have spread your prion worldwide, you need to focus on its survival. Evolve your prion's resistance to protect it from medical cures and health authorities.

  • Start with drug resistance, which allows you to resist medical cures.
  • Then evolve heat and cold resistance to survive in any climate.
  • Finally, evolve resistance to quarantine to continue spreading the prion despite isolation measures.

By following these strategies, you can effectively evolve your prion and win in Plague Inc. Remember that every game is different and you will need to adapt your strategy based on the situation.

How to manage obstacles in brutal mode

The brutal mode of Plague Inc. is extremely difficult and requires a very precise strategy to win. One of the main obstacles you will encounter are the preventive measures adopted by governments around the world.

Pay attention to news

To manage these obstacles, you must always be updated on world news. Every time a country discovers your disease, it will start taking preventive measures such as closing borders or quarantine. If you are always aware of the latest news, you can anticipate these measures and spread your disease before they become too severe.

Use the right symptoms

In addition, you must choose the right symptoms for your disease. Some symptoms may attract the attention of scientists and governments, while others may go unnoticed. For example, if you choose symptoms like "cough" or "fever", they are likely to be quickly detected by health authorities and preventive measures taken. Instead, symptoms like "nausea" or "headache" may not attract attention and allow you to spread the disease more easily.

Exploit mutations

Finally, exploit the mutations of your disease to overcome obstacles. Mutations can make your disease more resistant to treatments or drugs, allowing you to spread it without hindrance. However, you must be careful not to attract the attention of scientists and governments with too obvious mutations.

  • Constantly monitor world news
  • Choose the right symptoms for your disease
  • Exploit mutations to overcome obstacles

Conclusion and final tips

The brutal mode of Plague Inc. can be extremely difficult, but with the right strategy and planning, you can still win with the prion. Remember that it is important to spread your disease around the world as quickly as possible, but also maintain a low lethality to avoid attracting too much attention.

Start by investing in symptoms and air transmission to rapidly spread your disease. Then move on to water and parasite transmission to reach areas of the world that may be difficult to reach otherwise.

Remember to constantly monitor the global research level and use your DNA points to prevent countries from finding a cure. Also, try to avoid countries closing their borders or developing a cure for your disease.

Finally, do not despair if you fail on your first attempt. Try again with a different strategy and continue adapting to evolving circumstances. With a little luck and perseverance, you will succeed in winning with the prion in brutal mode.

  • Spread your disease quickly using airborne symptoms and transmission
  • Invest in water and parasite transmission to reach hard-to-reach areas
  • Constantly monitor the global research level and use your DNA points to prevent countries from finding a cure
  • Prevent countries from closing their borders or developing a cure for your disease
  • Retry with a different strategy if you fail on your first attempt

By following these tips, you'll be able to win with the prion on brutal mode and become a true Plague Inc. expert.

Conclusion:

Winning on brutal mode in Plague Inc. is not easy, but by following these tips, you can significantly increase your chances of success. Always remember to spread your disease quickly, constantly monitor the global research level, and adapt to evolving circumstances. With a bit of luck and perseverance, you'll be able to win with the prion on brutal mode!

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Michael Anderson - Software Engineer

My name is Michael Anderson, and I work as a computer engineer in Midland, Texas.

My passion is sharing my knowledge in various areas, and my purpose is to make education accessible to everyone. I believe it is essential to explain complex concepts in a simple and interesting way.

With GlobalHowTo, I aim to motivate and enrich the minds of those who want to learn.