How to win with the Nano Virus in brutal mode in Plague Inc.
Plague Inc. is a strategic simulation video game in which the player takes on the role of a pathogen that seeks to spread worldwide, killing the entire human population. The game has a series of modes, including the "brutal" mode, which represents a particularly challenging challenge for players.
In the "brutal" mode, the game becomes extremely challenging because the nations of the world are much faster in responding to the epidemic and try to find a cure for the disease. In addition, weather conditions can affect the spread of the disease.
To win in "brutal" mode of Plague Inc., it is necessary to have a solid strategy and adapt quickly to changing situations. This requires an in-depth knowledge of the mechanics of the game and the different options available to the player.
- Objective: The main objective of the game is to spread the virus globally and kill all human population before a cure is found.
- Disease stages: The disease goes through several stages during gameplay, such as incubation stage, symptom stage, and final stage where death occurs.
- Player abilities: The player has various abilities at their disposal, such as ability to transmit disease through water or air, ability to evolve to become more lethal and drug-resistant, and ability to control symptoms of disease so as not to attract attention from health authorities.
In summary, Plague Inc. is a challenging and stimulating game that requires a solid strategy and in-depth knowledge of game mechanics to win in "brutal" mode. With good planning and adaptation to changing situations, it is possible to spread the virus worldwide and kill all human population.
General strategies to win in brutal mode
The brutal mode of Plague Inc. requires an aggressive and fast-paced strategy to win. Here are some general strategies to follow:
- Choose the right type of virus: To win in brutal mode, you'll need to choose a virus that spreads quickly and can infect people without being noticed too soon. Viruses like the Nano Virus, Bio-weapon, and Apocalypse are good choices.
- Focus on transmission: You need to focus on virus transmission from the start. Choose symptoms that increase transmission such as coughing, sneezing, and sweating. This way the virus will spread more easily.
- Try to avoid international attention: International attention can lead to greater efforts to find a cure. Try to keep your virus under control and not attract attention to it until you have already infected enough people.
- Increase lethality gradually: You don't necessarily have to kill all infected people from the start. Gradually increase the lethality of the virus when you have already infected many people, so that it can spread even more easily.
By following these general strategies, you should have a better chance of winning with the Nano Virus in Plague Inc's brutal mode. Good luck!
The peculiarities of the Nano Virus and its spread around the world
The Nano Virus is a particularly insidious pathogen, capable of spreading rapidly and causing irreparable damage. Unlike other types of viruses present in Plague Inc., the Nano Virus has some peculiarities that make it even more dangerous.
Speed of spread
The Nano Virus spreads incredibly quickly, enough to infect the entire global population in very little time. This factor makes it particularly difficult to contain, especially if action is not taken promptly.
Hidden symptoms
Unlike other viruses, the Nano Virus does not present obvious symptoms in the early stages of infection. This means that patients can remain asymptomatic for days or even weeks, spreading the pathogen without realizing it.
Rapid mutations
The Nano Virus mutates very quickly, making it difficult to create an effective vaccine. Additionally, mutations can lead to new symptoms or resistance to drugs used to combat it.
Global spread
Due to its high speed of spread and hidden symptoms, the Nano Virus can quickly spread worldwide. Once the infection has spread globally, it becomes extremely difficult to contain.
- To counter the Nano Virus, it is essential to act promptly and constantly monitor the pathogen's spread.
- Additionally, it is important to invest in research to develop an effective vaccine against this particularly insidious disease.
How to deal with cures and symptoms of the Nano Virus
Once your Nano Virus has spread worldwide, you will have to face the challenge of cures and symptoms. There are some things to keep in mind to cope with this situation.
Dealing with cures
Cures can be very challenging to deal with for your Nano Virus. However, there are some ways to cope with this situation:
- Mutate rapidly: When you see a country working on a cure, immediately mutate your virus so that the cure no longer works. This will give you valuable time to further spread your virus.
- Attack research centers: If you are advanced enough in the game, you may want to directly attack research centers to slow down the development of the cure.
- Choose your strategy: Depending on the type of game you're playing, you may choose to focus on spreading your virus rather than its lethality. In this case, it's possible to let people recover from the virus, but make sure to spread it quickly enough so they don't have time to develop a cure.
Dealing with Symptoms
The symptoms of the nano virus can be very difficult to manage. Here are some tips for dealing with this situation:
- Choose the right symptoms: When choosing which symptoms to develop, try to focus on those that don't attract too much attention. For example, you may want to avoid symptoms like "cough" or "fever," as these will draw the attention of governments and media.
- Mutate quickly: Like with cures, mutate your virus so that the symptoms aren't detected by authorities. This way you can continue to spread the virus without being discovered.
- Be careful with lethality: If your strategy is to kill all humans on the planet, then you can develop highly lethal symptoms. However, if you just want to spread your virus without killing too many people, you need to be careful about which symptoms you choose to develop.
Remember that dealing with cures and symptoms of the nano virus can be very challenging. However, by following these tips and adapting your strategy to the circumstances, you can increase your chances of winning the game!
Final Tips for Winning with Nano Virus in Brutal Mode
After following the above tips, there are some things you can do to increase your chances of winning with the nano virus in brutal mode:
- Be aggressive: Don't be afraid to attack the most populous and wealthy countries from the beginning of the game. This way, you can spread the virus worldwide faster and prevent stronger nations from developing a cure.
- Use airborne transmission: Airborne transmission is a very effective way to spread the virus worldwide. Make sure to invest enough evolution points to unlock it as soon as possible.
- Use lethal mutations: Lethal mutations can help you kill humans faster and prevent them from developing a cure. However, make sure not to overdo it with lethal mutations, otherwise you risk killing all humans too early and losing the game.
- Keep an eye on cure research: Regularly check the status of cure research and try to prevent it using your special abilities or investing evolution points in resistance to cure.
- Experiment: Don't be afraid to experiment and try different strategies to win with the nano virus in brutal mode. Each game is different and requires a unique strategy.
In summary, to win with the nano virus in brutal mode: be aggressive, use airborne transmission, use lethal mutations, keep an eye on cure research, and experiment with different strategies.
Conclusion
Winning with the Nano Virus in Brutal mode can be difficult, but by following these tips you will have a greater chance of success. Remember that each game is different and requires a unique strategy. Experiment and have fun as you try to destroy humanity with your micrometric virus!

Michael Anderson - Software Engineer
My name is Michael Anderson, and I work as a computer engineer in Midland, Texas.
My passion is sharing my knowledge in various areas, and my purpose is to make education accessible to everyone. I believe it is essential to explain complex concepts in a simple and interesting way.
With GlobalHowTo, I aim to motivate and enrich the minds of those who want to learn.





